Publications by authors named "A Maslova"
Danio rerio, commonly known as zebrafish, is an established model organism for the developmental and cell biology studies. Although significant progress has been made in the analysis of the D. rerio genome, cytogenetic studies face challenges due to the unclear identification of chromosomes.
View Article and Find Full Text PDFLampbrush chromosomes, with their unusually high rate of nascent RNA synthesis, provide a valuable model for studying mechanisms of global transcriptome up-regulation. Here, we obtained a whole-genomic profile of transcription along the entire length of all lampbrush chromosomes in the chicken karyotype. With nuclear RNA-seq, we obtained information about a wider set of transcripts, including long non-coding RNAs retained in the nucleus and stable intronic sequence RNAs.
View Article and Find Full Text PDFWe have previously shown that 5-arylaminouracil derivatives can inhibit HIV-1, herpesviruses, mycobacteria, and other pathogens through various mechanisms. The purpose of this study was to evaluate the potential of 5-arylaminouracils and their derivatives against leukemia, neuroblastoma, and glial brain tumors. 5-Aminouracils with various substituents and their 5'-norcabocyclic and ribo derivatives were screened for cytotoxicity against two neuroblastoma cell lines (SH-SY5Y and IMR-32), K-562 lymphoblastic cells, HL-60 promyeoloblastic cells, and low-passage variants of well-differentiated glioblastoma multiforme (GBM5522 and GBM6138).
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- Scientists looked at how treating sewage sludge (waste from toilets) affects the levels of harmful metals and chemicals in farming soils and crops.
- They found that using processed sludge helped reduce 'bad' metals in crops, like arsenic and copper, and made sure the crops were safe to eat.
- The study showed that treating sludge can lower harmful chemicals significantly, but more research is needed to see how it works with different soils and plants.
Article Synopsis
- * This research investigates how high levels of naturally occurring Tl (50 mg/kg) affect soil microbes in the Buus region of Switzerland, focusing on both forest and meadow soils derived from Thallium-rich dolomite rock.
- * Findings reveal that, despite high Tl concentrations, soil bacterial richness was mostly unaffected, with only meadow soils showing reduced diversity, indicating soil microbes have a significant resilience to extreme Tl contamination.