Publications by authors named "A Martin-Bastida"
Article Synopsis
- * Results showed significant improvement in motor symptoms on the treated side, with reductions in MDS-UPDRS III scores and improvements in rigidity, bradykinesia, and tremor.
- * Most adverse events were mild, with some temporary severe cases; however, cognitive functions remained stable, indicating the procedure's potential benefits without significant long-term risks.
MR-guided focused ultrasound (MRgFUS) has proven its efficacy and safety for the treatment of essential tremor (ET) and/or Parkinson's disease (PD). However, having a cardiac pacemaker has been considered an exclusion criterion for the use of MRgFUS. Only 2 patients with a cardiac pacemaker treated with MRgFUS have been previously reported, both treated using 1.
View Article and Find Full Text PDFBackground: Factors predicting clinical outcomes after MR-guided focused ultrasound (MRgFUS)-thalamotomy in patients with essential tremor (ET) are not well known.
Objective: To examine the clinical outcomes and their relationship with patients' baseline demographic and clinical features and lesion characteristics at 6-month follow-up in ET patients.
Methods: A total of 127 patients were prospectively evaluated at 1 (n = 122), 3 (n = 102), and 6 months (n = 78) after MRgFUS-thalamotomy.
The role of astrogliosis in the pathology of brain aging and neurodegenerative diseases has recently drawn great attention. Imidazoline-2 binding sites represent a possible target to map the distribution of reactive astrocytes. In this study, we use C-BU99008, an imidazoline-2 binding sites-specific PET radioligand, to image reactive astrocytes in healthy controls and patients with established Parkinson's disease dementia.
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