Publications by authors named "A Marruchella"

Background And Objective: Sarcoidosis can manifest with atypical findings on chest computed tomography (CT). Cysts are a rare manifestation of lung sarcoidosis. The aim of the study was to describe a series of patients with cystic sarcoidosis and their clinical-radiological characteristics and progression.

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Article Synopsis
  • Sarcoidosis and hypersensitivity pneumonitis (HP) are two separate lung diseases that both involve granulomatous inflammation but have distinct clinical and radiological features.
  • The case study presents two patients who were simultaneously diagnosed with both conditions: one man with occupational exposure and high serum ACE levels suggesting sarcoidosis, and one woman with mold exposure and enlarged lymph nodes.
  • The findings highlight the potential for overlapping characteristics between the two diseases, indicating that they may sometimes occur together due to a shared underlying biological factor.
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Idiopathic pulmonary fibrosis (IPF), the most lethal form of interstitial pneumonia of unknown cause, is associated with a specific radiological and histopathological pattern (the so-called "usual interstitial pneumonia" pattern) and has a median survival estimated to be between 3 and 5 years after diagnosis. However, evidence shows that IPF has different clinical phenotypes, which are characterized by a variable disease course over time. At present, the natural history of IPF is unpredictable for individual patients, although some genetic factors and circulating biomarkers have been associated with different prognoses.

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