Publications by authors named "A Marquis"
Background: Multiparametric magnetic resonance imaging (mpMRI) is pivotal in prostate cancer (PCa) diagnosis, but some clinically significant (cs) PCa remain undetected. This study aims to understand the pathological and molecular basis for csPCa visibility at mpMRI.
Methods: We performed a retrospective matched-pair cohort study, including patients undergoing radical prostatectomy (RP) for csPCa (i.
Article Synopsis
- Targeted microwave ablation (TMA) shows promise as a safe and effective treatment for localized prostate cancer, based on a pilot trial involving 11 patients.* -
- No severe complications were reported, and a significant percentage of patients exhibited no cancer in the treated area after follow-up, although new cancer foci were found in some cases.* -
- The study acknowledges limitations such as a small sample size, short follow-up duration, and absence of a comparison group, but supports the potential of TMA combined with fusion imaging for prostate cancer therapy.*
Background: The COVID-19 pandemic has prompted significant changes in healthcare, particularly affecting psychiatric and psychological Consultation-Liaison (CL) services in general hospital settings.
Aim: To assess the effects of COVID-19-related restrictions on utilization of psychiatric and psychological CL services in Northeast Italy during 2020, and to compare it to the use of services in the previous year (2019).
Methods: The study collected data on psychiatric and psychological consultations in 2019 and 2020 from a hospital database.
Follow-up on patients with initial negative mpMRI target and systematic biopsy for PI-RADS ≥ 3 lesions - an EAU-YAU study enhancing prostate cancer detection.
Prostate Cancer Prostatic Dis
November 2024
Purpose: To investigate the detection and predictors of prostate cancer (PCA) and clinically significant prostate cancer (csPCA) in patients with positive multiparametric MRI (mpMRI) followed by a negative MRI - guided target biopsy (TB) and systematic biopsy (SB).
Materials And Methods: This retrospective multicenter study included 694 patients from 10 tertiary referral centers with an initial positive mpMRI (PI-RADS ≥ 3) and negative results on both MRI-TB and SB. Patients were classified into three groups based on follow-up: Group 1 (prostate re-biopsy without new mpMRI), Group 2 (standardized second prostate mpMRI and subsequent re-biopsy), and Group 3 (follow-up with mpMRIs and biopsy based on clinical and radiological triggers).
Surveillance after Focal Therapy - a Comprehensive Review.
Prostate Cancer Prostatic Dis
October 2024
Background: to date, no standardized, evidence-based follow-up schemes exist for the monitoring of patients who underwent focal therapy (FT) and expert centers rely mainly on their own experience and/or institutional protocols. We aimed to perform a comprehensive review of the most advantageous follow-up strategies and their rationale after FT for prostate cancer (PCa).
Methods: a narrative review of the literature was conducted to investigate different follow-up protocols of FT for PCa.