The dorsolateral prefrontal cortex (dlPFC) is increasingly targeted by various noninvasive transcranial magnetic stimulation or transcranial current stimulation protocols in a range of neuropsychiatric and other brain disorders. The rationale for this therapeutic modulation remains elusive. A model is proposed, and up-to-date evidence is discussed, suggesting that the dlPFC is a high-level cortical centre where uncertainty management, movement facilitation, and cardiovascular control processes are intertwined and integrated to deliver optimal behavioural responses in particular environmental or emotional contexts.
View Article and Find Full Text PDFThis study investigates a series of surface-active ionic liquids (SAILs), including both imidazolium monocationic and dicationic compounds. These compounds are promising candidates, as they combine unique surface properties with antimicrobial activity, aligning with modern trends in chemistry. The research encompasses synthesis, thermal analysis, and topographical assessment, focusing on the impact of the amphiphilic cationic moiety, alkyl chain length, and the spatial relationship between the imidazolium ring and the phenyl substituent on the compounds' physicochemical behavior.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
November 2024
Most hyperbaric medicine reports concentrate on the patient and his morbidities. In addition to the well-known indications for hyperbaric oxygen therapy (HBOT), we cannot discount possible side effects. Among medical staff regularly exposed to hyperbaric conditions the best described so far is decompression sickness.
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