Publications by authors named "A Marcinkowska"

The dorsolateral prefrontal cortex (dlPFC) is increasingly targeted by various noninvasive transcranial magnetic stimulation or transcranial current stimulation protocols in a range of neuropsychiatric and other brain disorders. The rationale for this therapeutic modulation remains elusive. A model is proposed, and up-to-date evidence is discussed, suggesting that the dlPFC is a high-level cortical centre where uncertainty management, movement facilitation, and cardiovascular control processes are intertwined and integrated to deliver optimal behavioural responses in particular environmental or emotional contexts.

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This study investigates a series of surface-active ionic liquids (SAILs), including both imidazolium monocationic and dicationic compounds. These compounds are promising candidates, as they combine unique surface properties with antimicrobial activity, aligning with modern trends in chemistry. The research encompasses synthesis, thermal analysis, and topographical assessment, focusing on the impact of the amphiphilic cationic moiety, alkyl chain length, and the spatial relationship between the imidazolium ring and the phenyl substituent on the compounds' physicochemical behavior.

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  • Mineralocorticoid receptors are found in various parts of the brain, and although aldosterone levels in the brain are lower than in the bloodstream, they can still lead to significant clinical effects.
  • High aldosterone levels, seen in conditions like primary aldosteronism, are linked to secondary hypertension and can negatively affect cerebral functions, contributing to anxiety and depression, which are tied to cognitive impairments.
  • The mini review highlights the known effects of aldosterone on brain health while addressing the uncertainties surrounding its influence on cognitive functions independent of blood pressure.
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Most hyperbaric medicine reports concentrate on the patient and his morbidities. In addition to the well-known indications for hyperbaric oxygen therapy (HBOT), we cannot discount possible side effects. Among medical staff regularly exposed to hyperbaric conditions the best described so far is decompression sickness.

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  • Tuberous sclerosis complex (TSC) is a condition linked to epilepsy and cognitive challenges, and recent studies using diffusion tensor imaging (DTI) aim to explore how it affects brain structure in adults with and without epilepsy.* -
  • The research involved 37 TSC patients, split into those with epilepsy and those without, compared to a matched control group, utilizing MRI DTI to analyze white matter integrity.* -
  • The findings revealed significant differences in white matter abnormalities between patients with TSC and epilepsy versus those without, with the former group showing more extensive and severe changes in their brain structure.*
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