Water pollution is a significant worldwide problem, and research studies in this field are still in progress to find strategies for removing pollutants from water. Among the others, adsorption process seems to exhibit several advantages, especially when biomasses are in use. This work proposes biochar from olive pomace pyrolysis for adsorbing contaminants from water, in synergistic combination with TiO, for constituting water-stable and recyclable composite chitosan-based sponges.
View Article and Find Full Text PDFObjective: This study investigated metformin as a sensitizer for radiotherapy in oral squamous cell carcinoma (OSCC) to reduce the radiation intensity. It evaluated the drug's effect on Chromatin Assembly Factor-1 (CAF-1) expression, whose high levels correlate with worse prognosis of this cancer.
Methods: The effects of metformin, alone and with radiotherapy, were evaluated on CAL27 (HPV-) and SCC154 (HPV+) OSCC cells.
Int J Mol Sci
August 2024
In the last years, 5-pyrazolyl ureas and 5-aminopyrazoles have been investigated for their antiangiogenetic properties and their potential interaction with the ubiquitous Ca binding protein Calreticulin. Based on the structure of the active compounds I and GeGe-3, novel 5-arylamino pyrazoles 2 and 3 were synthesized through a stepwise procedure. In MTT assays, all the new derivatives proved to be non-cytotoxic against eight different tumor cell lines, normal fibroblasts, and endothelial cells.
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