Ameliorative potential of Populus alba leaf powder against hexaflumuron exposure in Nile tilapia: immune-antioxidant, biochemical, histological, and transcriptomic analysis.

Contamination of the aquatic bodies with pesticides is a serious issue that hinders the aquaculture industry worldwide. Preventing aquatic pollution is a challenge, and finding eco-friendly strategies could help to overcome such a problem. Herein, we studied the antagonistic potential of dietary fortification of white poplar (Populus alba; PA) leaf powder against chronic hexaflumuron (HX) toxicity in Nile tilapia (Oreochromis niloticus).

Innovative perspectives on the discovery of small molecule antibiotics.

Antibiotics are essential to modern medicine, but multidrug-resistant (MDR) bacterial infections threaten their efficacy. Resistance evolution shortens antibiotic lifespans, limiting investment returns and slowing new approvals. Consequently, the WHO defines four innovation criteria: new chemical class, target, mode of action (MoA), and lack of cross-resistance.

An intelligent multi-attribute decision-making system for clinical assessment of spinal cord disorder using fuzzy hypersoft rough approximations.

The data for diagnosing spinal cord disorder (SCD) are complex and often confusing, making it difficult for established diagnostic techniques to yield reliable results. This issue frequently necessitates expensive testing to get an accurate diagnosis. However, the diagnostic process can be enhanced by integrating theoretical frameworks that resemble fuzzy sets, which better manage complexity and uncertainty.

Linear dicentric chromosomes in bacterial natural isolates reveal common constraints for replicon fusion.

Unlabelled: Multipartite bacterial genome organization can confer advantages including coordinated gene regulation and faster genome replication but is challenging to maintain. lineages often contain a circular chromosome (Ch1), a linear chromosome (Ch2), and multiple plasmids. We previously observed that in some stocks of the lab model strain C58, Ch1 and Ch2 were fused into a linear dicentric chromosome.