Economic impact of selective use of contrast for routine follow-up MRI of patients with multiple sclerosis.

Background And Purpose: Imaging and autopsy studies show intracranial gadolinium deposition in patients who have undergone serial contrast-enhanced MRIs. This observation has raised concerns when using contrast administration in patients who receive frequent MRIs. To address this, we implemented a contrast-conditional protocol wherein gadolinium is administered only for multiple sclerosis (MS) patients with imaging evidence of new disease activity on precontrast imaging.

Unruptured Arteriovenous Malformations in the Multidetector Computed Tomography Era: Frequency of Detection and Predictable Failures.

Objectives: While hemorrhage arising from ruptured arteriovenous malformations (AVMs) is usually evident on multidetector non-contrast computed tomography (NCCT), unruptured AVMs can be below the limits of detection. We performed a retrospective review of NCCT of patients with a proven diagnosis of unruptured AVM to determine if advances in CT technology have made them more apparent and what features predict their detection.

Material And Methods: Twenty-five NCCTs met inclusion criteria of having angiography or MR proven AVM without hemorrhage, prior surgery, or other CNS disease.

Determination of Programmable Shunt Setting Using CT: Feasibility Study.

Background: Programmable shunts can be adjusted to optimize CSF diversion in patients with hydrocephalus without the need for re-operation. Currently, all shunts incorporate radiopaque markers so that their setting can be determined on skull X-ray images. The purpose of this study was to evaluate whether the shunt setting could also be determined ex vivo and in vivo using the data from a standard head CT scan since one is nearly always obtained when patients with VP shunts present with new symptoms that could be due to shunt malfunction.