Publications by authors named "A Makatsarya"
Objectives: To explore whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can affect umbilical vein blood flow (UVBF) and fetal cardiac function.
Methods: Prospective case-control study of consecutive pregnancies complicated by SARS-CoV-2 infection during the second half of pregnancy matched with unaffected women. Measurements of UVBF normalized for fetal abdominal circumference (UVBF/AC), atrial area (AA) and ventricular sphericity indices (SI) were compared between the two study groups.
Article Synopsis
- The study investigates the evaluation and care provided to women suffering from unexplained recurrent pregnancy loss (RPL) or intra-uterine fetal death (IUFD), focusing on treatment options like low-molecular weight heparin (LMWH) and low-dose aspirin (ASA).
- Conducted across 12 hospitals in three countries from 2012 to 2019, the research included a cohort of women with a history of multiple pregnancy losses and aimed to identify factors influencing pregnancy outcomes.
- The results showed that 77% of the analyzed women had live births, with treatments prescribed differently based on whether they had thrombophilia, yet the effectiveness of the treatments remained inconclusive due to patient variability.
Article Synopsis
- * The main cause of FGR is placental insufficiency, which results in chronic fetal hypoxia, affecting the heart's blood flow dynamics differently in early and late cases.
- * In early onset FGR, blood flow is redirected to the brain and heart, while late FGR leads to changes in the fetal heart's shape and function due to reduced umbilical vein flow.
Introduction: Our objective was to compare the fetal growth velocity and fetal hemodynamics in pregnancies complicated and in those not complicated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Material And Methods: Prospective case-control study of consecutive pregnancies complicated by SARS-CoV-2 infection during the second half of pregnancy matched with unaffected women. The z scores of head circumference, abdominal circumference, femur length, and estimated fetal weight were compared between the two groups.
Objective: There is a lack of evidence on whether to favor cerebroplacental ratio (CPR) or umbilicocerebral ratio (UCR) when assessing pregnancies at risk of fetal growth restriction. The Recent evidences highlight a significant heterogeneity in the methodology of previously published studies reporting reference ranges for Doppler indices, which may affect the clinical applicability of these charts. The aim of this study was to develop charts of UCR based upon a recently proposed standardized methodology and using quantile regression.
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