Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis.

During oogenesis, self-renewal and differentiation of germline stem cells (GSCs) must be tightly regulated. The female germline serves as an excellent model for studying these regulatory mechanisms. Here, we report that a previously uncharacterized gene , which we named , is essential for oogenesis and female fertility in .

Individual, Host-Vector Interactions, and Environmental Risk Factors for Malaria Among At-Risk Communities in Peninsular Malaysia: A Case-Control Study.

Highlighting the individual, host-vector interactions, and environmental risk factors for knowlesi malaria were consequential toward more focused and effective prevention and control strategies. This study aims to identify the individual, host-vector interactions, and environmental risk factors for Plasmodium knowlesi malaria among at-risk communities in Peninsular Malaysia. A case-control study was conducted involving laboratory-confirmed cases of P.

Acute toxicity profiling of medicinal herb leaf extract by conventional evaluations and proton nuclear magnetic resonance (NMR) metabolomics.

Background And Aim: Interest in the safety of herbal medicine is growing rapidly regarding knowledge and challenges in natural products. Hence, this study aimed to reveal the toxicological profile of , a traditional medicinal plant used in the treatment of various illnesses.

Experimental Procedure: Acute toxicity study was performed on female and male Sprague Dawley rats with a single oral administration of 2000 mg/kg BW of 70% ethanolic leaf extract, using a combination of conventional investigations and H-NMR-based metabolomics approaches.