Publications by authors named "A Majewski"

Recycling waste to produce liquid fuels for the automotive and aviation industries is a major global concern, especially in light of the ongoing energy crisis. Because waste is used in thermal conversion processes, the resulting liquid products often require additional processing to reduce their density and viscosity, and to remove oxygenated compounds or pollutants that hinder further utilization. Catalytic hydrogenolytic reactions such as hydrodeoxygenation (HDO) and hydrocracking (HC) have been extensively applied to upgrade pyrolysis oils.

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Selective C-H functionalization methods could provide a valuable tool for synthesizing different steroid derivatives, which is essential not only in contexts of developing novel synthetic methodology but also as a direct way for gathering the analogues needed for studying the structure-activity relationships and obtaining biologically active compounds. The review discusses recent examples of steroid C-H functionalization to various C-X derivatives (C-O, C-C, C-N, C-S, and C-halogen) using available methods emphasizing their scope and limitations.

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Article Synopsis
  • The Global Program to Eliminate Lymphatic Filariasis aims to find better management strategies for lymphedema caused by lymphatic filariasis, focusing on the WHO-recommended Essential Package of Care (EPC) which includes skincare, limb elevation, exercise, and more.
  • A recent double-blind study conducted in Kerala, India, involving 200 patients with lymphedema, tested the effectiveness of doxycycline against a placebo, with assessments made over a two-year period.
  • The study found no significant difference between the doxycycline and placebo groups, but confirmed that the EPC significantly helps lymphedema patients by reducing acute episodes and improving their overall quality of
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Article Synopsis
  • - Lymphedema (LE), a serious condition resulting from lymphatic filariasis, is primarily treated through limb hygiene and local care, with a study exploring doxycycline's potential benefits.
  • - A multicenter trial in Mali tested doxycycline (200 mg/day) against a placebo for 6 weeks in patients with LE stages 1-3, measuring the disease's progression over 24 months.
  • - Results showed no significant difference in LE progression between the doxycycline and placebo groups, but both experienced reduced acute adenolymphangitis attacks; doxycycline was well tolerated but not more effective than hygiene alone.
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Cardiovascular diseases (CVDs) are often linked to ageing and are the major cause of death worldwide. The declined proliferation of adult stem cells in the heart often impedes its regenerative potential. Thus, an investigation of the proliferative potential of adult human cardiac stem cells (hCSCs) might be of great interest for improving cell-based treatments of cardiovascular diseases.

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