Publications by authors named "A Maieron"
Endosc Int Open
November 2024
Article Synopsis
- The study examined colorectal cancer (CRC) screening participation and quality in Austria, revealing significant gaps in meeting guideline quality metrics among screening colonoscopies.
- Out of 10,239 eligible employees, only 23% participated in stool-based screening, with a 24% positivity rate for tests; follow-up for colonoscopy was high at 84%.
- The adenoma detection rate (ADR) varied widely based on the type of endoscopist, with most European Society of Gastrointestinal Endoscopy quality indicators not being met, highlighting the need for improved quality assurance in CRC screening.
Hepatol Commun
November 2024
Article Synopsis
- Immunotherapy combinations are the standard treatment for advanced hepatocellular carcinoma (HCC), with growing evidence supporting lenvatinib as a strong first-line option.
- A retrospective study analyzed 412 patients treated with either atezolizumab/bevacizumab (AZ/BV) or lenvatinib (LEN) across 18 European hospitals, revealing that those on AZ/BV experienced longer progression-free survival.
- Despite comparable survival rates between the two treatments overall, AZ/BV posed a higher risk of liver issues in patients with pre-existing liver function impairment, highlighting the need for careful patient monitoring.
Article Synopsis
- The ELIMINATE project aimed to reconnect individuals in Eastern Austria with previously documented hepatitis C virus (HCV) infections to medical care, supporting global elimination goals set by the WHO.
- Researchers reviewed lab records from 2008 to 2020, identifying 5,695 individuals, but faced challenges such as 34% having died and 13% lacking contact information.
- Ultimately, they successfully contacted 617 individuals, leading to a 64.3% treatment initiation rate, and confirmed an HCV cure in 326 people, demonstrating the effectiveness of targeted outreach strategies in addressing HCV.
Article Synopsis
- - Detection and diagnosis of colon polyps are crucial for preventing colorectal cancer, and AI technologies can improve colonoscopy effectiveness through computer-aided detection (CADe) and diagnosis (CADx) systems.
- - The REAL-Colon dataset offers a large collection of 2.7 million native video frames from real-world colonoscopy, featuring 350,000 expert-annotated bounding boxes, which provide a more realistic dataset compared to existing down-sampled images.
- - This dataset includes comprehensive patient and procedural data, promoting transparency and enabling researchers to develop and benchmark more accurate AI algorithms for improved colonoscopy outcomes.
Front Med (Lausanne)
October 2023
Article Synopsis
- Felty's syndrome, described in 1924, is characterized by a combination of rheumatoid arthritis, splenomegaly, and leucopenia, presenting ongoing diagnostic and treatment challenges nearly a century later.
- The syndrome poses significant risks due to neutropenia, leading to life-threatening infections, with various suggested mechanisms like anti-neutrophil antibodies and neutrophil consumption complicating understanding.
- Current treatment options mainly include methotrexate and rituximab, but evidence for alternatives is limited, highlighting a need for further research and updated treatment approaches.
