Publications by authors named "A Magotra"
This study revealed the presence of single nucleotide polymorphisms in the CXCR1 gene and their association with performance traits and mastitis incidence in Murrah buffalo. The targeted SNP rs211042414 (T > C) at the g.106216468 locus in partial exon 2 of the CXCR1 gene was genotyped using PCR amplification and restriction enzyme digestion by Alu I, Bsa I, Dde I, Ava I, Hind III, EcoRV, Hae III, and Hae II restriction enzymes.
View Article and Find Full Text PDFUnderstanding the genetic basis of growth and metabolic traits in sheep is crucial for improving production efficiency and sustainability. The current study aimed to estimate the genetic influences, both direct and maternal, on growth rate and Kleiber's ratio traits in Harnali sheep using pedigree data under Bayesian inference. The data pertained to 2404 animals spanned over 24 years (1998-2021).
View Article and Find Full Text PDFGenetic evaluation of early reproductive traits of Harnali sheep.
Trop Anim Health Prod
September 2024
Article Synopsis
- The study investigates early reproductive traits in Harnali crossbred ewes, focusing on age at first lambing, weight at first lambing, and first lambing interval using 24 years of data.
- Methods used include least-squares modeling and Bayesian estimation to analyze genetic parameters, revealing low direct heritability for these traits but some maternal influence.
- The findings suggest that improving reproductive efficiency requires better management practices, particularly in feeding and breeding, while also accounting for maternal effects.
Epigenetic mechanisms, such as DNA methylation, histone modifications and non-coding RNA molecules, play a critical role in gene expression and regulation in livestock species, influencing development, reproduction and disease resistance. DNA methylation patterns silence gene expression by blocking transcription factor binding, while histone modifications alter chromatin structure and affect DNA accessibility. Livestock-specific histone modifications contribute to gene expression and genome stability.
View Article and Find Full Text PDFThe present study explored the association between a point mutation (g.857G>A) in the IGF-1 gene and performance traits in Harnali Sheep. Genomic DNA was extracted from 110 Harnali sheep using an Automated Maxell RSC DNA/RNA purification system.
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