Publications by authors named "A Maged"
Adropin/Tirzepatide Combination Mitigates Cardiac Metabolic Aberrations in a Rat Model of Polycystic Ovarian Syndrome, Implicating the Role of the AKT/GSK3β/NF-κB/NLRP3 Pathway.
Int J Mol Sci
December 2024
Polycystic ovarian syndrome (PCOS) is a multifaceted metabolic and hormonal disorder in females of reproductive age, frequently associated with cardiac disturbances. This research aimed to explore the protective potential of adropin and/or tirzepatide (Tirze) on cardiometabolic aberrations in the letrozole-induced PCOS model. Female Wistar non-pregnant rats were allotted into five groups: CON; PCOS; PCOS + adropin; PCOS + Tirze; and PCOS + adropin+ Tirze.
View Article and Find Full Text PDFObjectives: To evaluate the efficacy and safety of Carbetocin compared to oxytocin in prevention of postpartum hemorrhage (PPH) after low-risk cesarean delivery (CD).
Search Strategy: Screening of Medline, Web Of Science, Scopus, Google scholar, and clinical trials registry till January 2024 using the key words related to carbetocin, blood loss, PPH, Cesarean section and their MeSH terms was done.
Selection Criteria: This study included all RCTs conducted on women with low risk for developing PPH after CD and compared the administration of carbetocin to oxytocin without any language limitation.
Article Synopsis
- The study aimed to evaluate the effectiveness of misoprostol before hysteroscopy in women who have never given birth (nulliparous).
- A total of 13 studies involving 1,528 participants were analyzed, comparing misoprostol to various alternatives including placebo and other medications.
- Results indicated mixed outcomes on cervical dilation and pain levels, with a significant reduction in time for cervical dilatation (p=0.03), but no strong evidence for improved ease of dilation or reduced preoperative pain.
Article Synopsis
- - Disposing of non-biodegradable waste like polyvinylidene fluoride (PVDF) creates global environmental and economic challenges, prompting the need for innovative recycling solutions.
- - This study focuses on using discarded PVDF ultrafiltration membranes to produce char through optimized pyrolysis, achieving a yield of 31.3% with a specific iodine number that indicates high carbon quality.
- - Various analyses confirmed the breakdown of fluorinated bonds and identified beneficial crystalline structures in the PVDF, suggesting that the resulting char has significant potential for industrial and environmental applications within a circular economy framework.