Synthesis, Physicochemical Properties, and Ion Recognition Ability of Azulene-Based Bis-(Thio)Semicarbazone.

Azulene-1,3-bis(semicarbazone), , and azulene-1,3-bis(thiosemicarbazone), , were synthesized by the acid-catalyzed condensation reactions of semicarbazide and thiosemicarbazide, respectively, with azulene-1,3-dicarboxaldehyde in stoichiometric amounts. Compounds and were identified by high-resolution mass spectrometry and characterized by IR, H-NMR, C-NMR, and UV-vis spectroscopic techniques. Crystal structure determination of azulene-1,3-bis(thiosemicarbazone) shows that the thiosemicarbazone units exhibit a -closed conformation, with both arms oriented in the same direction and adopting an configuration with respect to the imine linkages.

A Synthetic Approach for Oxadiazole-Decorated Azobenzene Photoswitches.

This work reports the design and synthesis of novel oxadiazole-decorated azobenzenes, structural analysis of the resulting compounds and behavior under light irradiation. The synthetic strategy involved constructing amino functionalized heterocyclic key intermediates which were used either to yield electrophilic diazonium salts able to react with phenol moieties or as nucleophilic partners in Bayer-Mills reaction with nitroso-substituted derivatives. The amino-derived oxadiazole intermediates were investigated by absorption and emission spectroscopy providing blue and green emitted light.

Novel Derivatives of Nitrobenzofurazan with Chromogenic and Fluorogenic Properties.

Five new derivatives were obtained utilizing 4-chloro-7-nitrobenzofurazan (NBD-chloride) in combination with furfurylamine, adamantylamine, aminohippuric acid, phenylalanine, and dehydroabietylamine. These derivatives were then subjected to a comparative analysis of their physical, chemical, and certain biological properties alongside two analogous and known compounds derived from the glycine and 4-amino-TEMPO free radical.

Homo- and heterometallic complexes of Zn(II), {Zn(II)Au(I)}, and {Zn(II)Ag(I)} with pentadentate Schiff base ligands as promising anticancer agents.

Two families of homo- and heterometallic complexes, [ZnL(μ-OH)(HO)](ClO), [ZnL(μ-OH)(HO)](ClO), [ZnL(μ-OH)(HO)](ClO), 1∞[{LZn(μ-OH)}{μ-[Ag(CN)]}](ClO), [{LZn(μ-OH)}{μ-[Au(CN)]}{[Au(CN)]}](ClO)·HO, 1∞[{LZn(μ-OH)}(HO){μ-[Ag(CN)]}](ClO)·THF·0.5MeOH, 1∞[{LZn(μ-OH)}(HO){μ-[Au(CN)]}](ClO)·THF·HO, and 1∞[{LZn(μ-OH)}{μ-[Ag(CN)]}][Ag(CN)]·HO, respectively, have been synthesized and characterized. The Schiff bases used as ligands were obtained by condensation reactions of 2,6-diformyl--cresol with ,-dimethyl-ethylenediamine (HL), 2-aminomethyl-pyridine (HL), and 2-aminoethyl-pyridine (HL), respectively.

Biological Evaluation and Structural Analysis of Some Aminodiphenylamine Derivatives.

4-Aminodiphenylamino derivatives were investigated for their antioxidant and hydrophobicity character, together with other biological measurements, such as antimicrobial and antibiofilm activity. Among these nine compounds used, we obtained novel derivatives via reaction of the starting material with NBD-chloride. Therefore, we performed a full structural analysis for these compounds, i.