Background: The diagnostic yield of invasive coronary angiography (ICA) in patients with chronic coronary syndromes (CCS) in contemporary practice is uncertain.
Aims: We investigated the value of an advanced invasive diagnosis (AID) strategy combining angiography and intracoronary testing.
Methods: AID-ANGIO is an all-comers, prospective, multicentre study enrolling CCS patients referred for ICA.
Background: Despite the advances in the last decades for treatment of ischemic heart disease, women continue to experience poorer prognosis than men and currently, there is a gap in knowledge regarding the optimal revascularization strategy in women.
Objective: Compare the long-term outcomes of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for the treatment of stable ischemic heart disease in women.
Methods: A systematic search was conducted including randomized clinical trials (RCTs) comparing PCI with drug-eluting stents with CABG.
Importance: The differences between the use of fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR) in the long term are unknown.
Objective: To compare long-term outcomes of iFR- and FFR-based strategies to guide revascularization.
Design, Setting, And Participants: The DEFINE-FLAIR multicenter study randomized patients with coronary artery disease to use either iFR or FFR as a pressure index to guide revascularization.