Publications by authors named "A MOTOYAMA"
The skin is constantly exposed to environmental sensory stimuli, which may include harmful volatiles and small hydrophobic molecules. However, the skin's protective mechanism against the latter agents is unclear. Here, we demonstrate that odorant binding protein 2A (OBP2A) protects epidermal keratinocytes against cytotoxic small hydrophobic molecules.
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- - The study aimed to identify challenges in measuring respiratory rates among healthcare workers and improve their behavior to enhance patient care by observing and implementing multi-nudges in a hospital setting.
- - Results showed that initially low respiratory rate measurement rates increased significantly after introducing visual prompts, while barriers like time constraints and equipment issues were also identified.
- - The findings suggest that applying behavioral science principles can effectively change healthcare practices, ultimately leading to more accurate patient evaluations and better healthcare quality.
Objective: Intensive studies have revealed that pleiotropic melanocytic factors are associated with age-spot formation. Dysfunctional keratinocyte differentiation is thought to be an upstream cause of age-spot formation. Although it has been shown that keratinocyte differentiation is mediated by the cell-cell contact factor E-cadherin, its involvement in age-spot formation remains unknown.
View Article and Find Full Text PDFAims: Osteosarcoma (OS) is the most common primary malignant bone sarcoma among children and adolescents. Treatment is based on neo-adjuvant and adjuvant chemotherapy, using the standard drugs cisplatin, methotrexate, doxorubicin, and ifosfamide (IFO). Due to the high capacity of tumor resistance, the current work aimed to analyze genes related to cycle control and cell differentiation in OS cells sensitive to and with induced resistance to IFO.
View Article and Find Full Text PDFBilayer graphene (BLG) has a two-dimensional (2D) interlayer nanospace that can be used to intercalate molecules and ions, resulting in a significant change of its electronic and magnetic properties. Intercalation of BLG with different materials, such as FeCl, MoCl, Li ions, and Ca ions, has been demonstrated. However, little is known about how the twist angle of the BLG host affects intercalation.
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