Publications by authors named "A MILANO"
Background: The authorization of new therapeutic indications for drugs already reimbursed by the Italian National Health Service (NHS) represents a matter of importance. This study aims to estimate the additional discount attributed to the extension of indications (EoIs) to explore the potential correlation between spending and negotiated discounts and to find specific factors (determinants) that impact on discount.
Methods: The study focused on drugs approved in Italy between 2003 and 2017 with at least four therapeutic indications, including the first approved and EoIs, with follow-up extended until 2021 to acquire all the information on the negotiation process that has been completed.
Heart failure is a serious and challenging medical condition characterized by the inability of the heart to pump blood effectively, leading to reduced blood flow to organs and tissues. Several underlying causes may be linked to this, including coronary artery disease, hypertension, or previous heart attacks. Therefore, it is a chronic condition that requires ongoing management and medical attention.
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- The study emphasizes a holistic approach to managing vector-borne diseases (VBDs) by integrating ecological, biological, and social factors, known as One Health (OH), which requires collaboration among institutions and communities.
- A literature review identified 13 relevant peer-reviewed articles, highlighting the importance of cross-sector collaboration in resource sharing and knowledge exchange to address VBDs effectively.
- The research proposes an OH model that outlines enabling factors for successful multisectoral interventions, aiming to assist decision-makers and stakeholders in enhancing their governance strategies for VBD prevention and preparedness.