Publications by authors named "A M Venkatesan"
Purpose: The human papillomavirus (HPV) is a significant cause of cervical cancer. We hypothesized that detecting viral cell-free HPV DNA (cfDNA) before, during, and after chemoradiation (chemoRT) could provide insights into disease extent, clinical staging, and treatment response.
Experimental Design: Sixty-six patients with locally advanced cervical cancer were enrolled between 2017 and 2023.
Article Synopsis
- - There is a significant need to assess the knowledge and training gaps among infectious disease (ID) physicians regarding encephalitis, specifically autoimmune encephalitis.
- - A survey was conducted among European ID specialists, with 201 respondents indicating that 64% dealt with infectious encephalitis, while only 7.5% focused on autoimmune cases.
- - Many physicians reported low confidence in recognizing (60%), diagnosing (71%), and treating (85%) autoimmune encephalitis, highlighting the demand for standardized guidelines from ESCMID for better management practices (89%).
Article Synopsis
- Exfoliation Syndrome (XFS) is an age-related condition affecting the eye, leading to the accumulation of fibrillar materials that can cause Exfoliation Glaucoma (XFG), a form of secondary open-angle glaucoma.
- XFG is linked to neurodegenerative disease features and characterized by mitochondrial dysfunction, including impaired energy production and increased reactive oxygen species (ROS) in affected cells.
- Research shows that treating XFG patient-derived cells with agents like Urolithin A and Nicotinamide Ribose can help improve mitochondrial function and reduce ROS, suggesting a potential therapeutic approach for XFG.
The European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) is one of the world's leading sources of public biomolecular data. Based at the Wellcome Genome Campus in Hinxton, UK, EMBL-EBI is one of six sites of the European Molecular Biology Laboratory, Europe's only intergovernmental life sciences organization. This overview summarizes the latest developments in services that EMBL-EBI data resources provide to scientific communities globally (https://www.
View Article and Find Full Text PDFA 63-year-old man, with a history of melanoma and basal cell carcinoma, presented with progressive right-sided facial numbness, vertical diplopia, and headache. Brain MRI revealed leptomeningeal enhancement of multiple cranial nerves and an enhancing mass-like lesion along the anterolateral surface of the pons and midbrain. Subsequent brain biopsy demonstrated the final diagnosis.
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