The understanding of psoriasis has shifted to emphasize the complex role of the IL-17 family of cytokines, particularly IL-17RA, in the disease's development and progression.
IL-17RA is a vital component that enables Th17 cells to connect innate and adaptive immune responses and is crucial for signaling all IL-17 isoforms except IL-17D.
The article provides an overview of the biological functions of IL-17 cytokines and receptors, focusing on IL-17RA's impact on psoriasis and related health issues, as well as its implications for current and future treatments.
Ossifying fibromyxoid tumors (OFT) of soft parts are very rare neoplasms recently described by Enzinger et al. (1). They usually present as well-circumscribed, slow-growing, asymptomatic subcutaneous masses.