Frequency and Clinical Features of Space Headache Experienced by Astronauts During Long-Haul Space Flights.

Background And Objectives: Few anecdotal cases and 1 small retrospective study during short-duration space missions suggest that headache may occur early in flight, as part of the space motion syndrome. Whether headaches may also occur at later stages of space flights is unknown. We aimed to prospectively characterize the incidence, timing, clinical features, and management of space headaches during long-duration flights.

Early recognition of characteristic conventional and amplitude-integrated EEG patterns of seizures in SCN2A and KCNQ3-related epilepsy in neonates.

Purpose: Early recognition of seizures in neonates secondary to pathogenic variants in potassium or sodium channel coding genes is crucial, as these seizures are often resistant to commonly used anti-seizure medications but respond well to sodium channel blockers. Recently, a characteristic ictal amplitude-integrated electroencephalogram (aEEG) pattern was described in neonates with KCNQ2-related epilepsy. We report a similar aEEG pattern in seizures caused by SCN2A- and KCNQ3-pathogenic variants, as well as conventional EEG (cEEG) descriptions.

Valentin Magnan and Sergey Korsakov: French and Russian pioneers in the study of alcohol abuse.

This study focuses on two outstanding psychiatrists: the Frenchman Valentin Magnan (1835-1916) and the Russian Sergey Korsakov (1854-1900). Their international renown is primarily associated with their investigations into health consequences of alcohol consumption; they were pioneers in this field, and happened to know each other well. The similarities and differences are shown in social and scientific approaches adopted by these two scientists.