Multi-omics integration and immune profiling identify possible causal networks leading to uterine microbiome dysbiosis in dairy cows that develop metritis.

Background: Cows that develop metritis experience dysbiosis of their uterine microbiome, where opportunistic pathogens overtake uterine commensals. An effective immune response is critical for maintaining uterine health. Nonetheless, periparturient cows experience immune dysregulation, which seems to be intensified by prepartum over-condition.

Brain metabolic subtypes in Long Covid individuals from a Brazilian cohort.

Background: The Coronavirus disease 2019 (COVID‐19), caused by SARS‐CoV‐2, is one of the biggest health concerns of the century. Long COVID is one of the major sequelae from the infection and include persistent neurological manifestations. Brain images study suggest that Long COVID patients present distinct brain metabolic alterations.

Characterizing plasma biomarkers of Alzheimer’s disease in three non‐human primate species: marmosets, titi monkeys, and capuchins.

Background: Studies of aging in non‐human primates are important to elucidate primate‐specific mechanisms underlying human aging, including pathological trajectories like Alzheimer’s disease (AD). Evidence of AD‐like brain aging has been reported across the primate order including amyloid beta (AB) deposits, but blood‐based biomarkers are less well‐studied. The goal of this project was to explore the use of validated assays for plasma biomarkers in two new non‐human primate species: coppery titi monkeys (Plecturocebus cupreus) and brown capuchins (Sapajus apella).

Brain Glucose Metabolism Changes in Long‐COVID: A Brazilian Cohort Study.

Background: The COVID‐19 pandemic is a public health crisis, and its lasting consequences are not yet fully understood. Epidemiological data suggest that low‐ and middle‐income countries, such as Brazil, will bear a considerable burden of COVID‐19‐related comorbidities. Individuals who have survived COVID‐19 often report persistent symptoms, including neurological manifestations such as brain fog.