Publications by authors named "A M Tari"
Background: Regular physical activity (PA) is important for reducing the risk of chronic diseases and improving overall health. Activity Quotient (AQ) is a novel metric that translates heart rate during PA into a weekly score, providing an objective measure of an individual's PA. We prospectively examined the association of AQ with cancer and cardiovascular (CVD) mortality outcomes, the two major causes of death, in a Taiwanese population.
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- The study aimed to find the cardiorespiratory fitness (CRF) levels necessary for older adults (70-77 years) to reduce their risk of death, hypothesizing that higher peak oxygen uptake (VO) would be protective.
- The research included a cohort of 1,565 older adults in Norway, who underwent VO testing and were monitored for all-cause mortality over five years.
- Results indicated that lower VO levels (less than 26.5 mL/kg/min for men and 22.2 mL/kg/min for women) significantly increased the risk of death, emphasizing the need for maintaining or improving CRF in later life.
Article Synopsis
- The study examined the link between Personal Activity Intelligence (PAI) scores and coronary heart disease (CHD) in a large group of healthy adults in Norway, emphasizing the impact of physical activity intensity on CHD risk.
- Researchers analyzed data from over 40,000 participants, finding that those with higher PAI scores (51-99 and ≥ 100) had a significantly lower risk of experiencing fatal and non-fatal CHD during a median follow-up of 13.1 years.
- The inclusion of PAI in traditional risk assessments improved the ability to classify individuals' CHD risk, highlighting that a PAI score above 50 is notably protective against CHD.
Neurogenesis persists throughout adulthood in the hippocampus and contributes to specific cognitive functions. In Alzheimer's disease (AD), the hippocampus is affected by pathology and functional impairment early in the disease. Human AD patients have reduced adult hippocampal neurogenesis (AHN) levels compared to age-matched healthy controls.
View Article and Find Full Text PDFBackground: Microglia and inflammation play a significant role in Alzheimer's disease (AD). Physical exercise and peripheral signals can influence microglial activity in the brain. Modulating the inflammatory response in the brain may provide therapeutic approaches for AD.
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