[The Molecular and Genetic Mechanisms of Sex Determination in Poplar].

The study of molecular and genetic mechanisms of sex determination in the poplar is of interest not only in the fundamental science, but also in the applied research. In landscaping of large settlements, it is advisable to use male individuals of the Populus genus due to their hypoallergenicity and increased resistance to environmental pollution, stress conditions, and pathogens. However, sex determination in poplars is complicated by the complex genetic structure of the sex-determining region of the genome (SDR).

The Effect of Meclofenoxate on the Transcriptome of Aging Brain of Annual Killifish.

Annual fish of the genus are promising models for aging research. reproduces typical aspects of vertebrate aging, including hallmarks of brain aging. Meclofenoxate (MF) is a well-known compound that can enhance cognitive performance.

The study of the effect of thiazoline ammonium 4-chlorophenyl-2-hydroxy-4-oxo-2-butenoate on blood coagulation upon intragastric and subcutaneous administration.

We studied the effects of subcutaneous and intragastrical administration of synthesized compound thiazoline ammonium 4-chlorophenyl-2-hydroxy-4-oxo-2-butenoate (FS 169) on blood clotting in vitro and in vivo in rabbits. Compound FS 169 significantly prolongs clotting time in vitro; its activity is comparable with that of heparin. When administered subcutaneously, the substance is rapidly absorbed and significantly reduces blood clotting by 102.

[Comparative study of the effects of 4-chlorophenyl-2-hydroxy-4-oxo-2-butenoate and heparin on blood coagulation].

The purpose of this work investigation to study the effect of 4-chlorophenyl-2-hydroxy-4-oxo-2-butenoate (thiazoline ammonium butenoate, compound FS 169) and heparin on the coagulation of whole rabbit blood in vitro and in vivo. The effects of heparin and FS 169 were investigated using a Minilab 701 coagulometer. Citrated (3.