Publications by authors named "A M Slagle"
Article Synopsis
- - Sensor-based digital health technology (DHT) uses sensors to improve understanding of patient health by providing data on functioning both in and out of clinical trials, enhancing the patient experience for medical product development.
- - The paper outlines recommendations for defining sensor-based functional outcomes (SBFOs), the necessary evidence to support their use in decision-making, and future directions for this emerging field.
- - Successful SBFO development relies on a combination of expertise in patient engagement, measurement science, and analytics, while addressing challenges such as identifying meaningful health concepts and establishing thresholds for change, making SBFOs valuable alongside traditional clinical outcome assessments.
Background: People with chronic hepatitis B (CHB) commonly experience social and self-stigma. This study sought to understand the impacts of CHB-related stigma and a functional cure on stigma.
Methods: Adults with CHB with a wide range of age and education were recruited from 5 countries and participated in 90-minute qualitative, semi-structured interviews to explore concepts related to CHB-associated stigma and its impact.
Continued fossil fuel emissions will increase CO concentrations in the atmosphere and could require removal of 10 Gt of CO per year or more to reach IPCC global climate goals. Large-scale construction of direct air capture (DAC) hubs to scrub CO from the atmosphere paired with geological storage is a prominent approach to potentially meet this target. We consider one location for theoretical scale-up of a DAC hub: the Kerguelen plateau in the Southern Indian Ocean which has high-potential renewable energy resources (wind) and large volumes of basalt rock for mineral storage.
View Article and Find Full Text PDFBackground: In support of UCB pharmaceutical research programs, the aim of this research was to implement a novel process for patient involvement in a multidisciplinary research group to co-create a clinical outcome assessment strategy to accurately reflect the experience of people living with early-stage Parkinson's. Patient experts were an integral part of the decision-making process for patient-reported outcome (PRO) research and instrument development.
Methods: In partnership with two patient organizations (Parkinson's UK and the Parkinson's Foundation), 6 patient experts were recruited into a multidisciplinary research group alongside clinical, patient engagement and involvement, regulatory science, and outcome measurement experts.