Publications by authors named "A M Silvan Sen"

Purpose: To report OCTA (Optical coherence tomography angiography) characteristics of bilateral MacTel type 1 with capillary obliteration.

Method: Colour fundus photo (CFP), OCT angiography (OCTA), Fundus fluorescein angiography (FFA), Fundus autofluorescence (FAF).

Result: We describe three cases of bilateral MacTel Type 1 with a special emphasis on OCTA characteristics.

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Article Synopsis
  • Human mesenchymal stem cells (hMSCs) react to mechanical stimuli like stiffness and fluid viscosity, which impacts their behavior.
  • In environments with high fluid viscosity, hMSCs favor an osteogenic (bone-forming) phenotype over an adipogenic (fat-forming) one by altering their actin structure and enhancing cellular activities.
  • This research highlights fluid viscosity as an important factor that not only influences hMSC differentiation but also encourages a more immunosuppressive M2 macrophage phenotype.
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Background: Plasma cell myeloma (PCM) is a common adult hematological neoplasm of terminally differentiated B-cells resulting in accumulation of monoclonal plasma cells. PCM is heterogeneous disease with survival time varies from months to years, determined by age, stage, cytogenetics abnormalities, and treatment response. There is conflicting evidence in role of immunophenotype as a prognostic indicator.

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We investigate the dynamical phases and phase transitions arising in a classical two-dimensional anisotropic XY model under the influence of a periodically driven temporal external magnetic field in the form of a symmetric square wave. We use a combination of finite temperature classical Monte Carlo simulation, implemented within a CPU+GPU paradigm, utilizing local dynamics provided by the Glauber algorithm and a phenomenological equation-of-motion approach based on relaxational dynamics governed by the time-dependent free energy within a mean-field approximation to study the model. We investigate several parameter regimes of the variables (magnetic field, anisotropy, and the external drive frequency) that influence the anisotropic XY system.

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