Publications by authors named "A M Sesterhenn"

Article Synopsis
  • Multiple sclerosis (MS) is a complex central nervous system disease that involves both degeneration and inflammation, influenced by various mediators including the protein lipocalin 2 (LCN2).
  • In this study, researchers found that a specific type of astrocytes produces LCN2 in MS lesions and investigated its effects using different mouse models of MS that mimic different aspects of the disease.
  • The results suggest that LCN2 may help protect against the loss of oligodendrocytes and limit inflammation in MS, though the exact role and contributions of different brain cells remain unclear.
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Objective: During the first months of the COVID-19 pandemic, there was a significant reduction in the frequency of visits to healthcare institutions. This circumstance influenced the timely diagnosis and subsequential initiation of therapy in almost all specialties. The aim of the present study is to evaluate a hypothetical change in health awareness with regard to outpatient consultations of ENT physicians in Germany.

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Objective: COVID-19 pandemic has impact on the oncology service system for tumor patients. What is the view of head and neck cancer patients (HNC) on this situation and which coping strategies were developed?

Material & Methods: In study 1 PRIO asked 433 tumor patients regarding their impressions/fears during the lockdown between April 15 and May 15, 2020 (online, standardized questionnaire). In 2 study 292 tumor patients reported their pandemic-induced perceived changes and coping strategies by established questionnaires (WHO-5, MLQ, GrAw-7).

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Objective: The aim of the study was to investigate the relationship between the presence of a hearing aid (HA) and the occurrence of various disorders of the external ear, using data from ear, nose, and throat (ENT) practices in Germany from a nationwide, representative practice database.

Methods: In the period between 2012 and 2016, the incidences of disorders of the external ear (ICD-10 groups H60 and H61) in patients with HA prescriptions were compared retrospectively with a control group without HA prescriptions (1:1 matching).

Results: A total of 20,127 patients with HA prescriptions were compared with 20,127 controls.

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