Nongenomic Progesterone Receptors Mediated Bull Sperm Capacitation and Acrosome Reaction Are cAMP-PKA-Calcium Channel Dependent.

Progesterone (P4) secreted from the cumulus cells mediates nongenomic signalling in sperm cells and induces capacitation and acrosome reaction in the oviduct. The induction of these events in bull spermatozoa is not fully understood. Recently, we reported the presence of membrane nongenomic P4 receptors in bull spermatozoa and the involvement of P4-nongenomic signalling through the involvement of complex signalling pathways with cannabinoid receptors in the regulation of bull sperm capacitation and acrosome reaction.

Spatial Variation and Adaptive Responses of Tall-Type Field Peas (Pisum sativum L.) Across Indian Subcontinent.

Understanding crop performance across diverse agro-ecologies is crucial for developing region-specific breeding strategies. This multi-location study examined the impact of diverse environments on crop eco-phenology and genotype-by-environment interactions (GEI) of tall-type field pea breeding lines. Empirical methods were employed to identify strategic locations that support higher yields and unique genotypic traits.

Trends and outcomes of heart failure hospitalizations during COVID-19 pandemic.

Background: COVID-19 has affected many hospitalizations. In this study, we intended to understand the effects of COVID-19 pandemic on heart failure hospitalizations in the state of California.

Method: This study was a retrospective analysis of California State Inpatient Database during March to December of 2019 and 2020.