New immunoassays for MUC1 in breast cancer.

Eleven experimental immunofluorometric assays (IFMAs) were made using antibodies previously tested for epitope specificities. These assays were compared with six commercially available immunoassays. The clinical performance of these experimental assays was evaluated by analysing sera from 138 breast cancer patients and 105 female blood donors.

The applicability of the time/temperature superposition principle to brain tissue.

This paper deals with the mechanical characterization of brain tissue which behaves as a viscoelastic material. We focus on the linear viscoelastic behavior, which should apply for small strains at any strain rate, and demonstrate the applicability of the time/temperature superposition principle. This principle allows the opportunity to extend the range of shear rates for which the material is characterized, and makes the results applicable to impact conditions.

The influence of different boundary conditions on the response of the head to impact: a two-dimensional finite element study.

The objective of the present study is to gain a better understanding of the possible importance of skull-brain interface conditions, boundary conditions at the head-neck junction, and brain material properties when modeling the response of the human head to transient loadings. To that end, a two-dimensional plane strain finite element model of a para-sagittal section of a human head has been developed. The model comprises the brain and the skull, with the foramen magnum represented by a force-free opening.

A note on the reduced creep function corresponding to the quasi-linear visco-elastic model proposed by Fung.

For description of the visco-elastic behavior of soft biological tissues, Fung proposed a visco-elastic model formulated in terms of a relaxation function and corresponding relaxation spectrum. For the corresponding creep function, Fung proposed an expression which needs correction to obtain a consistent formulation. This creep function and the corresponding creep spectrum are derived in this note.