Publications by authors named "A M Salvatierra"
Objective: To explore the association of maternal characteristics, oxygenation, and mechanical ventilatory parameters with fetal and neonatal outcomes.
Methods: The present study was a multicenter, binational (Argentina/Colombia), prospective, cohort study, conducted in 21 intensive care units (ICUs) and including pregnant or postpartum patients with COVID-19 pneumonia requiring advanced respiratory support and their fetuses/neonates. Advanced respiratory support was defined as high-flow nasal cannula (HFNC), non-invasive ventilation (NIV) or invasive mechanical ventilation (IMV).
Disease severity and drought due to climate change present significant challenges to orchard productivity. This study examines the effects of spring inoculation with () on sweet cherry plants, cvs. Bing and Santina with varying defense responses, assessing plant growth, physiological variables (water potential, gas exchange, and plant hydraulic conductance), and the levels of abscisic acid (ABA) and salicylic acid (SA) under two summer irrigation levels.
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- Tissue metabolomics provides valuable insights into tissue physiology and tumor characteristics, but obtaining this information is invasive, expensive, and can delay patient care.
- Computed tomography (CT) is widely used but lacks detailed histological or prognostic information, and integrating metabolomic data with CT for improved classification and prognosis has not been extensively explored.
- This study introduces a deep learning framework (TMR-CT) that combines CT images with metabolite data, achieving effective histology classification and prognosis in lung cancer patients, outperforming traditional methods and offering a non-invasive alternative to conventional tissue analysis.
Altered splicing machinery in lung carcinoids unveils NOVA1, PRPF8 and SRSF10 as novel candidates to understand tumor biology and expand biomarker discovery.
J Transl Med
December 2023
Background: Lung neuroendocrine neoplasms (LungNENs) comprise a heterogeneous group of tumors ranging from indolent lesions with good prognosis to highly aggressive cancers. Carcinoids are the rarest LungNENs, display low to intermediate malignancy and may be surgically managed, but show resistance to radiotherapy/chemotherapy in case of metastasis. Molecular profiling is providing new information to understand lung carcinoids, but its clinical value is still limited.
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- The study analyzed 792 lung transplant surgeries to evaluate surgical complications and their effects on mortality and survival.
- Out of 769 patients reviewed, 32% experienced complications, leading to a significant increase in 30-day mortality rates among those patients.
- Key factors influencing complications included the type of transplant, patient age, and the necessity for extracorporeal support, which contributed to poorer long-term survival outcomes.