Publications by authors named "A M Ronchi"
: This study aims to evaluate whether the presence of isolated tumor cells (ITCs) correlates with specific stages of cutaneous melanoma, potentially shedding light on their prognostic significance and the paradoxical survival outcomes in stage IIIA. : This study analyzed cases of sentinel lymph node biopsies for cutaneous melanoma between 2021 and 2023. It included patients with CM diagnoses, available histological slides, and clinical information about the neoplasia stage.
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- The study explored the connection between Human Papillomavirus (HPV) and salivary gland tumors, which remains unclear in existing literature.
- The research involved 66 salivary gland lesions, using fine needle aspiration cytology to detect HPV-DNA, resulting in HPV found in two cysts and three metastatic carcinomas, but none in primary tumors.
- Ultimately, the study concluded that HPV did not play a role in primary salivary gland tumors, but its presence in intraglandular cysts suggests a new area for further investigation.*
Article Synopsis
- ! Antibiotics are given to 20%-30% of pregnant women, yet their impact on newborn immune development is not well understood, leading to increased susceptibility to sepsis in offspring of treated mothers.
- ! Newborn mice from antibiotic-treated mothers showed lower levels of immunoglobulin A (IgA) in breast milk and feces, leading to a weakened gut immune response and increased risks of gut bacteria entering the bloodstream.
- ! Restoring IgA production through treatments or using breast milk from untreated mothers improved immune profiles and offered protection against sepsis in pups, emphasizing the importance of breastfeeding in mitigating antibiotic effects.
Cardiac Amyloidosis: State-of-the-Art Review in Molecular Pathology.
Curr Issues Mol Biol
October 2024
Article Synopsis
- - Amyloidosis is a group of diseases caused by misfolded proteins that form harmful deposits in tissues, potentially affecting various organs, with amyloid fibrils being particularly resistant to breakdown.
- - The condition can result from factors like aging or genetic variations, harming organ function through disruptions in tissue structure and direct toxicity, which often leads to serious issues such as heart failure.
- - Diagnosing cardiac amyloidosis is challenging and usually involves tissue biopsies and special staining methods, while the review highlights key forms of the disease, their treatment, and the need for a collaborative approach to care.