Publications by authors named "A M Romoli"
Persons with disorders of consciousness (DoCs) may perceive pain without being able to communicate their discomfort. The Nociception Coma Scale (NCS) and its revised form (NCS-R) have been proposed to assess nociception in persons with DoCs. The main aim of this international multicenter study was to confirm (or not) our preliminary results and compare the NCS-R scores of standard stimulus (NCS-R-SS) to scores of personalized painful stimuli (NCS-R-PS).
View Article and Find Full Text PDFBackground: Participation represents the most relevant indicator of successful functioning after a severe traumatic brain injury (sTBI), since it correlates with a higher perceived quality of life by patients, their families, and healthcare professionals. Nevertheless, studies on Italian population are lacking.
Aim: The aim of this study was to evaluate the long-term participation and its early predictors in patients after a sTBI.
Article Synopsis
- The study aimed to differentiate between patients in a Minimally Conscious State (MCS) who show high-level behavioral responses (MCS+) and those who do not (MCS-), as this impacts treatment strategies.
- Researchers used low-density EEG recordings to assess brain activity in 57 MCS patients, applying graph metrics to analyze connectivity across different frequency bands.
- Results indicated that MCS- patients had less brain activity integration in the α band, while MCS- patients showed greater clustering in the δ band; machine learning models achieved a 79% accuracy in distinguishing between MCS+ and MCS-.
Objective: To prospectively investigate the evolution of the consciousness state and the cannula-weaning progression in patients with prolonged disorders of consciousness.
Design: Nonconcurrent cohort study.
Setting: A rehabilitation unit.
Consciousness can be defined as a phenomenological experience continuously evolving. Current research showed how conscious mental activity can be subdivided into a series of atomic brain states converging to a discrete spatiotemporal pattern of global neuronal firing. Using the high temporal resolution of EEG recordings in patients with a severe Acquired Brain Injury (sABI) admitted to an Intensive Rehabilitation Unit (IRU), we detected a novel endotype of consciousness from the spatiotemporal brain dynamics identified via microstate analysis.
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