Publications by authors named "A M Roguedas-Contios"

Article Synopsis
  • The study investigates the role of anti-Ro52/TRIM21 antibodies in primary Sjögren disease (SjD), focusing on how their presence correlates with various clinical and biological markers.
  • Two patient cohorts were analyzed, revealing that those with both anti-Ro52 and anti-Ro60 antibodies exhibited more severe symptoms, such as parotid enlargement and elevated inflammatory markers compared to other groups.
  • Transcriptomic analysis indicated that positive anti-Ro52/TRIM21 antibodies are associated with the activation of interferon pathways, suggesting a link to the disease's clinical manifestations.
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Introduction: The distinction between epidermal necrolysis [EN; including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and overlap syndrome] and erythema multiforme major (EMM) in children is confusing. We aimed to better describe and compare these entities.

Materials And Methods: This French retrospective multicentre study included children ≤18 years old referred for EN or EMM between 1 January 2008 and 1 March 2019.

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Background: Protein contact dermatitis has frequently been reported in case studies (usually in cases involving contact with seafood products), but there are very few descriptive series. The objectives of this present study were firstly to determine the incidence of protein contact dermatitis among fishermen in France and compare it with data from onshore work involving seafood exposure. Second, to discover what factors could explain any differences.

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