Publications by authors named "A M Ratsimbason"

Article Synopsis
  • Researchers isolated five new compounds called omphalines A-E from the leaves and twigs of Omphalea oppositifolia, along with a known compound using chromatography methods.
  • Omphaline A's structure was identified as a specific type of diterpenoid, characterized by unique double bonds and hydroxy groups.
  • The absolute configuration of omphaline A was confirmed by comparing its experimental electronic circular dichroism (ECD) spectrum with calculated ones.
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The global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this species is less responsive to conventional malaria control interventions aimed principally at P. falciparum. Approximately half of all malaria cases outside of Africa are caused by P.

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Two new pregnane glycosides, baseonemoside A and B, were isolated from the aerial parts of Baseonema acuminatum. Their structures were established as pregn-5-ene-3beta,16alpha,20(S)-triol 3-O-beta-D-cymaropyranosyl-(1-->4)-beta-D-digitoxopyranoside 20-O-beta-D-glucopyranosyl-(1-->2)-beta-D-digitalopyranoside 1 and pregn-5-ene-3beta,16alpha,20(S)-triol 3-O-beta-D-cymaropyranosyl-(1-->4)-beta-D-cymaropyranosyl-(1-->4)-beta-D-digitoxopyranoside 20-O-beta-D-glucopyranosyl-(1-->2)-beta-D-digitalopyranoside 2, respectively, on the basis of spectral evidence and chemical transformation.

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