The second most prevalent cause of mortality among women is breast cancer, and paclitaxel (PTX) is an effective drug for its treatment. The present work aims to develop patch-based poly(ε-caprolactone) (PCL) nanofibers incorporating PTX as a localized and sustained drug delivery system. The co-deposition of poly(vinyl alcohol) (PVA) fibers during electrospinning was allowed to improve water absorption by the scaffold, which in turn facilitated the release of drug molecules.
View Article and Find Full Text PDFThis paper presents a new probability distribution called the DUS Lindley distribution, created by applying the DUS transformation to the traditional Lindley distribution. The study provides an in-depth analysis of the distribution's statistical properties. These properties include a variety of statistical measures such as the probability density function, cumulative distribution function, failure rate, survival function, reverse hazard function, Mills ratio, mean residual life, mean past life, moments, conditional moments, characteristic function, order statistics, entropy measures, likelihood ratio test and Lorenz and Bonferroni curves.
View Article and Find Full Text PDFObjectives: The aim of this study was to compare the efficacy and safety of transdermal Fentanyl patch with oral Ketorolac for pain management in dry socket patients.
Study Design: Sixty patients who were diagnosed with dry socket (VAS > 40 mm) were recruited in this prospective randomized controlled trial. Patients were divided into two groups.