Publications by authors named "A M Pushpika Attanayake"

The present study aimed to synthesize, characterize, and determine the antidiabetic activity of Gmelina arborea and Spondias pinnata aqueous extract-encapsulated nanoliposomes (GAE-NL and SAE-NL). GAE-NL and SAE-NL were synthesized using modified emulsification and ultrasonication. The average size, polydispersity index, and zeta potential of GAE-NL and SAE-NL were 307 ± 2 nm, 0.

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Background: The hypertriglyceridemic waist (HTGW) phenotype is a simple measure to identify individuals at increased risk of metabolic syndrome (MetS) traits. The present study aimed to describe the HTGW prevalence, and its associations with MetS traits, and also determine the diagnostic potential of the mirror indices of HTGW phenotype to predict MetS and its components in community-dwelling adults with overweight or obesity in Southern, Sri Lanka.

Methods: In a cross-sectional study, 300 adults with excess body weight (body mass index >23 kg/m) were enrolled and examined for the HTGW phenotype (fasting plasma triglyceride concentration ≥1.

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Introduction: Chronic inflammation plays a key role in knee osteoarthritis pathophysiology and increases risk of comorbidities, yet most interventions do not typically target inflammation. Our study will investigate if an anti-inflammatory dietary programme is superior to a standard care low-fat dietary programme for improving knee pain, function and quality-of-life in people with knee osteoarthritis.

Methods And Analysis: The eFEct of an Anti-inflammatory diet for knee oSTeoarthritis study is a parallel-group, assessor-blinded, superiority randomised controlled trial.

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Aim: To optimise, and characterise gelatine nanoparticles (GNPs) encapsulating plant extracts and evaluate the glucose-lowering potential.

Methods: GNPs encapsulating plant extracts were prepared by desolvation method followed by adsorption. The GNPs were characterised by loading efficiency, loading capacity, particle size, zeta potential, SEM and FTIR.

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Bioactive compounds in medicinal plants are more susceptible to preventing oxidative stress. Encapsulation of herbal extracts has empowered the properties and characteristics of bioactive compounds. Nanoencapsulation allows the enhancement of the stability of extracts and targeted drug delivery.

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