Lactic acid in the vaginal milieu modulates the -host interaction.

Vulvovaginal candidiasis (VVC) is one of the most common infections caused by . VVC is characterized by an inadequate hyperinflammatory response and clinical symptoms associated with colonization of the vaginal mucosa. Compared to other host niches in which can cause infection, the vaginal environment is extremely rich in lactic acid that is produced by the vaginal microbiota.

Correlation of lipid profile APO A1 and APO B100 in chronic periodontitis patients leading to coronary artery disease.

Background: Increased attention has been focused on the association of periodontal disease with cardio-metabolic syndrome. Although the associations are multi-factorial, very few studies have explored the role of lipoprotein Apo A1 and Apo B100 with chronic periodontitis. Additionally, obstructive sleep apnea (OSA), a chronic multi-factorial respiratory disease, consists of a temporary decrease or cessation of breath for ≥ 10 seconds and leads to a reduction in blood oxygen saturation of more than 3% to 4% and/or neurological arousal.

Replacement of fishmeal with Quinoa Husk (Chenopodium quinoa) for mitigating multiple stresses in Pangasianodon Hypophthalmus.

The fishmeal is boon for aquaculture production in this recent pollution and climate change era. However, the demand of fishmeal is enhancing in many folds which needs to find alternative to fishmeal in cheap price. The present investigation addresses these issues with quinoa husk (QH).

Atrial Septal Defect and Percutaneous Closure: Healing the Heart From Within.

Early diagnosis and percutaneous closure of symptomatic adult atrial septal defects can enhance cardiac function and relieve symptoms. Thorough pre-procedural evaluation and diligent follow-up care are essential for achieving the best outcomes and ensuring long-term success.

Activation of δ-opioid receptors blocks allodynia in a model of headache induced by PACAP.

Background And Purpose: Pituitary adenylate cyclase activating polypeptide (PACAP) is a human migraine trigger that is being targeted for migraine. The δ-opioid receptor (δ-receptor) is a novel target for the treatment of migraine, but its mechanism remains unclear. The goals of this study were to develop a mouse PACAP-headache model using clinically significant doses of PACAP; determine the effects of δ-receptor activation in this model; and investigate the co-expression of δ-receptors, PACAP and PACAP-PAC1 receptor.