A Review of White Spot Lesions: Development and Treatment with Resin Infiltration.

Unlabelled: White spot lesions (WSLs) are demineralized lesions of the enamel that form in the presence of bacterial plaque, affecting the aesthetics by modifying the refractive index of the enamel, giving the characteristic "chalky" aspect. They have various causes, including fixed orthodontic treatments, improper hygiene, fluorosis and genetic factors.

Background/objectives: Considering the latest need for dental aesthetics and the popularization of fixed orthodontic treatments, the need to effectively treat WSLs has increased.

[COVID-19 vaccine safety: results of active surveillance at a sentinel site in ArgentinaSegurança das vacinas contra COVID-19: resultados da vigilância ativa em uma unidade sentinela da Argentina].

Objective: To analyze the results of surveillance of adverse events of special interest (AESI) within the context of the COVID-19 vaccination campaign at a sentinel site in Argentina. The retrospective (pre-vaccination) period was compared with the prospective (vaccination) period to identify safety signals.

Methods: Retrospective and prospective search for AESI based on ICD-10 hospital discharge codes.

Formation of hollow silver nanoparticles under irradiation with ultrashort laser pulses.

We have studied the formation of cavities in spherical silver nanoparticles embedded in silica, irradiated with fs laser pulses that produce an intense electronic excitation. Experimentally determined aspect ratio, i.e.

Mannitol for bowel preparation: Efficacy and safety results from the SATISFACTION randomised clinical trial.

Background: Bowel preparation represents a significant issue to high-quality colonoscopy. Oral mannitol requires a single dose, is of low volume, and has a pleasant taste and rapid action.

Aims: This SATISFACTION study compared single-dose (same day) oral mannitol 100 g/750 mL with standard split-dose PEG-ASC2 L (MoviPrep®).

Tetraspanins, GLAST and L1CAM Quantification in Single Extracellular Vesicles from Cerebrospinal Fluid and Serum of People with Multiple Sclerosis.

This study aimed to unravel the single tetraspanin pattern of extracellular vesicles (EVs), L1CAM and GLAST EV levels as diagnostic biomarkers to stratify people with multiple sclerosis (pwMS), specifically relapsing-remitting (RRMS) and primary progressive (PPMS). The ExoView platform was used to directly track single EVs using a clinically feasible volume of cerebrospinal fluid (CSF) and serum samples. This technology allowed us to examine the patterns of classical tetraspanin and quantify the levels of L1CAM and GLAST proteins, commonly used to immunoisolate putative neuron- and astrocyte-derived EVs.