Publications by authors named "A M Pello"

Article Synopsis
  • The study investigates the connection between inflammatory biomarkers and cardiovascular events in type 2 diabetes patients with stable coronary artery disease (CAD).
  • A total of 964 patients were analyzed, measuring inflammatory markers such as TNF-R1, GDF-15, and hsCRP, to see how these relate to acute ischemic events over a follow-up period of about 5.4 years.
  • Results showed that diabetic patients had higher inflammatory marker levels and a greater incidence of cardiovascular events, with TNF-R1 identified as an independent risk factor for these events specifically in diabetic patients.
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Article Synopsis
  • ATTR amyloidosis is a key cause of heart failure, and research aimed to find connections between cardiac function (measured by global longitudinal strain or GLS), biomarkers, and patient performance.
  • In a study involving 13 patients, various echocardiographic assessments, including GLS and a 6-minute walk test, were conducted alongside measuring inflammatory and cardiovascular biomarker levels.
  • Results showed significant correlations between GLS and NT-ProBNP, indicating better prognosis with more negative strain values, and that Klotho levels were linked to overall clinical performance in patients with ATTR amyloidosis.
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Introduction: The presence of non-coronary atherosclerosis (NCA) in patients with coronary artery disease is associated with a poor prognosis. We have studied whether NCA is also a predictor of poorer outcomes in patients undergoing coronary artery bypass grafting (CABG).

Materials And Methods: This is an observational study involving 567 consecutive patients who underwent CABG.

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Aims: Abnormalities of mineral metabolism (MM) have been related to cardiovascular disorders. There are no reports on the prognostic role of MM after an acute coronary syndrome (ACS). We aim to assess the prognostic role of MM after an ACS.

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Sodium-glucose cotransporter inhibitors (SGLT2i) have demonstrated a reduction in cardiovascular events in diabetes and heart failure (HF). The mechanisms underlying this benefit are not well known and data are contradictory. The purpose of this study is to analyse the effect of dapagliflozin on cardiac structure and function in patients with normal ejection fraction.

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