Publications by authors named "A M Paisley"
Introduction: Microvascular and macrovascular complications in type 1 diabetes (T1D) may be linked to endothelial stress due to glycaemic variability. Continuous glucose monitoring systems (CGMs) provide new opportunities to quantify this variability, utilising the amplitude of glucose change summated over time. The aim of this study was to examine whether this determination of glucose variability (GV) is associated with microvascular clinical sequelae.
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- The study investigates the long-term complications associated with type 1 diabetes (T1D) and the effectiveness of continuous glucose monitoring (CGM) in managing these issues.
- Data from 89 T1D patients over 18 months was analyzed, including average glucose levels and fluctuations, as well as glycated hemoglobin (HbA1c) results.
- Findings revealed an average blood glucose level of 10.3 mmol/l and a strong correlation (r = 0.82) between the glucose management index (GMI) and HbA1c measurements, indicating a relationship between glucose control and diabetes complications.
Transgenic plant production in monocotyledonous species has primarily relied on embryogenic callus induction from both immature and mature embryos as the pathway for plant regeneration. We have efficiently regenerated fertile transgenic wheat plants through organogenesis after -mediated direct transformation of mechanically isolated mature embryos from field-grown seed. Centrifugation of the mature embryos in the presence of was found to be essential for efficient T-DNA delivery to the relevant regenerable cells.
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