Publications by authors named "A M P Omuro"
Background: Glioma, the most prevalent primary brain tumor, poses challenges in prognosis, particularly in the high-grade subclass, despite advanced treatments. The recent shift in tumor classification underscores the crucial role of isocitrate dehydrogenase (IDH) mutation status in the clinical care of glioma patients. However, conventional methods for determining IDH status, including biopsy, have limitations.
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- This article reviews the importance of optimal initial management in primary CNS lymphoma (PCNSL) and its potential impact on long-term patient outcomes.
- Recent advances include using genomic analysis of CSF cell-free DNA for diagnosis and improved treatment options for younger patients, where chemotherapy has shown high cure rates.
- In contrast, older patients still face poor outcomes, prompting investigations into new therapies and consolidation options like low-dose radiation, while ongoing clinical trials aim to address their treatment needs.
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- The study investigates the connection between left atrial volume index (LAVI) changes after catheter ablation (CA) for persistent atrial fibrillation (AF) and the risk of long-term major adverse clinical events (MACE).
- Data from 150 patients were analyzed, finding that those with both high pre-CA and post-CA LAVI values experienced significantly more MACE.
- The findings suggest that evaluating both pre- and post-procedural LAVI can help predict patients' risk for long-term complications following CA.
The quality of radiation therapy (RT) treatment plans directly affects the outcomes of clinical trials. KBP solutions have been utilized in RT plan quality assurance (QA). In this study, we evaluated the quality of RT plans for brain and head/neck cancers enrolled in multi-institutional clinical trials utilizing a KBP approach.
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