Publications by authors named "A M Nyakabau"
Article Synopsis
- * A study involving 40 breast cancer patients in Zimbabwe found that many had genetic variants (polymorphisms) in CYP2D6 that affect drug metabolism, leading to lower endoxifen levels.
- * Results showed that 55% of participants had endoxifen concentrations below the therapeutic threshold, highlighting a significant relationship between CYP2D6 genetic variations and endoxifen levels (with specific statistical significance).
Purpose: Hypofractionated breast radiotherapy has been found to be equivalent to conventional fractionation in many clinical trials. Using data from the European Society for Radiotherapy and Oncology Global Impact of Radiotherapy in Oncology survey, we identified preferences for hypofractionation in breast cancer across World Bank income groups and the perceived facilitators and barriers to its use.
Materials And Methods: An international, electronic survey was administered to radiation oncologists from 2018 to 2019.
Purpose: Few sub-Saharan African studies have ascertained utilization for postmastectomy radiation (PMRT) for breast cancer, the second most common cancer among African women. We estimated PMRT utilization and identified predictors of PMRT receipt in Zimbabwe.
Methods: Retrospective patient cohort included non-metastatic breast cancer patients treated from 2014 to 2019.
Purpose: In sub-Saharan Africa, radiotherapy (RT) utilization and delivery patterns have not been extensively studied in patients with metastatic breast cancer.
Methods: A retrospective cohort study of female patients with metastatic breast cancer seen at Parirenyatwa Radiotherapy Centre in Zimbabwe from 2014 to 2018 was conducted. Demographics, pathology, staging, and treatment data were abstracted through chart review.
Background: Cervical cancer is the fourth most common cancer amongst women globally and it accounts for the majority of cancer deaths among females in Zimbabwe. The objective of this midterm review analysis was to identify the gaps and opportunities for cervical cancer prevention, diagnosis, treatment, and care to inform the next cervical cancer strategy in Zimbabwe.
Methods: A mixed methods approach was used for the midterm review.