Influence of one-year treatment with lovastatin on myocardial remodeling and ischemia in patients with coronary artery disease.

Objective: Emerging evidence assumes that statins have a benefit to influence the myocardial remodeling and ischemia in patients with coronary artery disease (CAD). Our aim was to investigate the possible and direct favorable effects of lovastatin on left ventricular (LV) systolic, diastolic function and myocardial ischemia in patients with CAD.

Methods: This randomized prospective study consisted of 83 patients (46 males; mean age 54.

[Association of the serum level of apolipoprotein E with coronary artery disease and carotid artery atherosclerosis in Kyrgyz men with dyslipidemia].

Aim: To study an association of the serum level of apolipoprotein E (apo-E) with risk factors for coronary heart disease (CHD), blood lipids and that with CHD and carotid artery (CA) atherosclerotic lesion in Kyrgyz men with dyslipidemia.

Subjects And Methods: One hundred and three Kyrgyz men, including 48 with CHD and 55 without this disease, were examined. A clinical examination was performed and blood lipid composition and serum glucose and apo-E levels were determined.

[Ethnic differences in apolipoprotein B levels in hyperlipidemia in Russian and Kirghiz populations].

Aim: To evaluate the levels of apolipoprotein B (apo-B) and coronary heart disease (CHD) risk factors in Russians and the Kirghiz with primary hyperlipidemia (PHL).

Material And Methods: Lipid spectrum of the blood (LDLP and HDLP cholesterol, total cholesterol, triglycerides), apo-B, CHD risk factors were studied in 60 Russian and 75 Kirghis patients with PHL aged 28 to 67 years (mean age 50.0 +/- 7.

[The use of corinfar in combined treatment of congestive heart failure at high altitude].

Altogether 52 patients with severe forms of congestive cardiac failure (CCF) developing as a result of rheumatic valvular heart diseases, were examined. The patients were divided into 2 groups: 35 living permanently in the lowlands (LL) and 17 living in the highlands (HL). All the patients received corinfar (nifedipine) as part of multimodality therapy at a single dose of 20 mg/m2 with 8-h intervals for 10 days.