Background: Wood ants are promising biocontrol agents in fruit plantations because they prey on pest insects and inhibit plant diseases. However, these ants also attend plant-feeding homopterans to harvest their honeydew secretions, thereby increasing their numbers. This problem can be solved by offering ants alternative sugar sources that are more attractive than honeydew.
View Article and Find Full Text PDFPurpose: The current clinical recommendations posit the deployment of specific approved radiolabeled prostate-specific membrane antigen-ligand positron emission tomography (PSMA PET) for detecting metastatic prostate cancer during primary staging. Nevertheless, the precise efficacy of such ligands in localizing intraprostatic tumours (index tumour) and T-staging is not well established. Consequently, the objective of this inquiry is to ascertain the diagnostic accuracy of PSMA-PET in the tumour staging of newly diagnosed prostate cancer by means of a meta-analysis that integrates studies utilizing histological confirmation as the reference standard.
View Article and Find Full Text PDFPaediatr Drugs
November 2022
Background: As part of the European Paediatric Regulation, the European Medicines Agency (former European Medicines Evaluation Agency) and the Paediatric Working Party (precursor for the Paediatric Committee) revised a priority list for studies on off-patent medicinal products in 2007 where a need for studies on paediatric medicinal products was emphasised.
Objectives: We aimed to evaluate the status of guidance for paediatric use in the Summary of Product Characteristics for medicinal products on the priority list as well as the presence and status of Paediatric Investigation Plans for these medicinal products.
Methods: We included active pharmaceutical ingredients on the priority list authorised through the centralised procedure and/or marketed in Denmark.
Objective: To determine whether preoperative staging of high-risk prostate cancer with F-sodium-fluoride (F-NaF) positron emission tomography (PET) reduces the risk of skeletal metastases.
Design: Nationwide, population-based cohort study using real-world data.
Setting: The study used national health registries, including all sites in Denmark from 2011 to 2018.