Publications by authors named "A M Mikheev"
Objective: Diffusion-weighted MRI is a technique that can infer microstructural and microcirculatory features from biological tissue, with particular application to renal tissue. There is extensive literature on diffusion tensor imaging (DTI) of anisotropy in the renal medulla, intravoxel incoherent motion (IVIM) measurements separating microstructural from microcirculation effects, and combinations of the two. However, interpretation of these features and adaptation of more specific models remains an ongoing challenge.
View Article and Find Full Text PDFBackground: Postacute Covid-19 patients commonly present with respiratory symptoms; however, a noninvasive imaging method for quantitative characterization of respiratory patterns is lacking.
Purpose: To evaluate if quantitative characterization of respiratory pattern on free-breathing higher temporal resolution MRI stratifies patients by cardiopulmonary symptom burden.
Study Type: Prospective analysis of retrospectively acquired data.
Article Synopsis
- Purpose of the study was to standardize quantitative imaging methods for tumors, specifically using DCE-MRI, through the OSIPI-DCE challenge to benchmark these methods.
- Methods involved creating a framework for evaluating DCE-MRI analysis submissions from the perfusion MRI community, focusing on glioblastoma quantification and requiring detailed reporting of procedures and software.
- Results showed significant variability in software performance, with scores indicating differences in accuracy, repeatability, and reproducibility, while highlighting the importance of standardized procedures for improving analysis consistency.
Background: Monoexponential apparent diffusion coefficient (ADC) and biexponential intravoxel incoherent motion (IVIM) analysis of diffusion-weighted imaging is helpful in the characterization of breast tumors. However, repeatability/reproducibility studies across scanners and across sites are scarce.
Purpose: To evaluate the repeatability and reproducibility of ADC and IVIM parameters (tissue diffusivity (D), perfusion fraction (F) and pseudo-diffusion (D)) within and across sites employing MRI scanners from different vendors utilizing 16-channel breast array coils in a breast diffusion phantom.
TWIST1 (TW) is a pro-oncogenic basic helix-loop-helix (bHLH) transcription factor and promotes the hallmark features of malignancy (e.g., cell invasion, cancer cell stemness, and treatment resistance), which contribute to poor prognoses of glioblastoma (GBM).
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