Publications by authors named "A M McCann"
Results from applying an advanced spatial-unfolding technique to outdoor-trial data acquired with a Silicon photomultiplier-based Compton Telescope for Safety and Security (SCoTSS) gamma imager during perimeter survey of a distributed La-140 source lying within a 500 m x 500 m exclusion zone are presented. A synthetic-data version of the experiment was also modelled using Monte Carlo simulations and reconstructed. For both experimental and synthetic data the method faithfully reproduces the shape of the activity distribution, and for synthetic data the total activity is reproduced as well.
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- A study explored the link between a bacterial metabolite, indole 3-acetate (3-IAA), and chemotherapy response in non-metastatic pancreatic ductal adenocarcinoma (PDAC) patients, building on previous findings in metastatic cases.
- Researchers measured 3-IAA levels in blood from 124 patients with locally advanced or borderline resectable PDAC before they started chemotherapy, primarily FOLFIRINOX.
- The results showed no significant association between pre-treatment 3-IAA levels and overall survival, suggesting that the positive effects seen in metastatic cases may not apply to non-metastatic patients, highlighting the need for further research.
Ergonomics in Facial Plastic and Reconstructive Surgery: A National Evaluation.
Facial Plast Surg Aesthet Med
December 2024
Objective: Mohs micrographic surgery (MMS) and subsequent reconstructive procedures for the treatment of facial nonmelanoma skin cancers (NMSCs) significantly impact quality of life (QoL). A validated patient-reported outcome measure (PROM) for patients who undergo Mohs reconstruction is not yet established. This study aims to systematically assess the quality of existing PROMs to determine their effectiveness in capturing the challenges faced after Mohs reconstruction for facial NMSC.
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