Secondary metabolites from Guill. and Perr. (Fabaceae).

The chemical investigation of the ethanol/water (7:3) extract of the roots of (Fabaceae) led to the isolation of one new labdane diterpenoid, microcarpin () and one new ceramide derivative, microcarpamide (), along with eight known secondary metabolites () including, 5-(carboxymethyl)-5,6,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalene-1-carboxylic acid (), microcarposide (), rhinocerotinoic acid (), 1,7-dihydroxy-6-methylxanthone (), ursolic acid (), 3,23-dihydroxylup-20(29)-en-28-oic acid (), alphitolic acid (), and stigmasterol glucoside (). The structures of these compounds were elucidated based on their spectroscopic data. Although compounds and are known, their crystalline structures are reported here for the first time.

Acute and sub-acute toxicity assessment of aqueous leaves extract of (Asteraceae) in Wistar rats.

Objectives: Several studies establish the therapeutic properties of various plants which are sometimes a source of minerals, vitamins and phytochemical compounds. However, many studies evoked potential toxic of some. In Cameroon, () is used in folk medicine to treat several diseases, but there are not much informations about its toxicity.

[The role of oxygen radicals in acute pancreatitis. Clinical and experimental results of therapy with free radical scavengers].

Numerous studies support the theory that oxygen free radicals (OR) are involved in the development of tissue damage in all forms of experimental acute pancreatitis. OR are generated in an early phase of the disease before tissue damage is detectable by histology. The pathomechanism that leads to this oxidative stress is not fully understood.