Publications by authors named "A M Mardanova"

We present the findings from the genome-sequencing project of GM2, sourced from rhizospheric soil and renowned for its lipopeptide production. The genome spans 4,216,713 base pairs with an average G + C content of 43,6%.

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We studied the effect of urinary urea concentration on the hemolysin production and cytotoxicity of the uropathogenic Morganella morganii strain MM 190. The highest hemolytic activity of M. morganii cultivated in urine with low urea concentration (23 and 82 mmol/liter) was observed between 3rd and 4th hours of post-inoculation, while in urine with standard urea level (117 mmol/liter), the activity was observed at 5th hour of post-inoculation.

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The intestinal and respiratory tracts of healthy individuals serve as habitats for a diverse array of microorganisms, among which Klebsiella oxytoca holds significance as a causative agent in numerous community- and hospital-acquired infections, often manifesting in polymicrobial contexts. In specific circumstances, K. oxytoca, alongside other constituents of the gut microbiota, undergoes translocation to distinct physiological niches.

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Article Synopsis
  • The study investigated how different growth media and aeration affect the hemolytic activity of uropathogenic Morganella morganii strain MM 190.
  • The highest hemolysis levels were recorded in LB (59%), DMEM with fetal bovine serum (62%), and urine (53%) during the exponential growth phase, while 2% urea hindered hemolysin production.
  • The hemolysin gene hlyA peaked in expression after 2 hours in LB medium, aligning with the observed hemolytic activity, indicating that the short hlyCA transcript is dominant in these conditions.
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