Publications by authors named "A M Mahtab"

Article Synopsis
  • Osteoporosis is caused by reduced osteoblast differentiation, largely due to overexpression of a specific gene.
  • A novel delivery method using chitosan-coated gold nanoparticles was developed to improve the effectiveness of siRNA, which typically has a short half-life and low transfection efficiency.
  • The engineered nanoparticles demonstrated an 80% reduction in the target sclerostin protein and significantly increased bone formation markers, suggesting a promising biocompatible treatment for osteoporosis.
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This research examined the characteristics of cold days and spells in Bangladesh using long-term averages (1971-2000) of maximum () and minimum temperatures () and their standard deviations (SD). Cold days and spells were calculated and their rate of change during the winter months (December-February) of 2000-2021 was quantified. In this research, a cold day was defined as when the daily maximum or minimum temperature is ≤-1.

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The aim of this study was to develop a database of historical cold-related mortality in Bangladesh using information obtained from online national newspapers and to analyze such data to understand the spatiotemporal distribution, demographic dynamics, and causes of deaths related to cold temperatures in winter. We prepared a comprehensive database containing information relating to the winter months (December to February) of 2009-2021 for the eight administrative divisions of Bangladesh and systematically removed redundant records. We found that 1249 people died in Bangladesh during this period due to cold and cold-related illnesses, with an average of 104.

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We announce the complete genome sequences of 12 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sublineage B.1.617.

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Rheumatoid arthritis (RA), an autoimmune inflammatory disorder is currently incurable. Methotrexate and Teriflunomide are routinely prescribed drugs but their uses are limited due to severe hepatotoxicity. Hyaluronic acid (HYA) is a targeting ligand for CD44 receptors overexpressed on inflamed macrophages.

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