Publications by authors named "A M M J Pieters"

Aim: Bronchiectasis (BE) is a disease defined by irreversible dilatation of the airway. Computed tomography (CT) plays an important role in the detection and quantification of BE. The aim of this study was three-fold: 1) to assess bronchus-artery (BA) dimensions using fully automated software in a cohort of BE disease patients; 2) to compare BA dimensions with semi-quantitative BEST-CT (Bronchiectasis Scoring Technique for CT) scores for BE and bronchial wall thickening; and 3) to explore the structure-function relationship between BA-method lumen dimensions and spirometry outcomes.

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  • A novel human circovirus, named HCirV-1, was discovered in a 66-year-old immunocompromised woman suffering from sudden hepatitis.
  • Researchers found HCirV-1 genetic material in the patient's liver cells and also in her blood, stool, and urine over an extended period.
  • HCirV-1 is recognized as an emerging human pathogen that can persist in individuals with weakened immune systems.
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Dilution is a standard fluid operation widely employed in the sample preparation process of many bio(chemical) assays. It serves multiple essential functions such as sample mixing with certain reagents at specific dilution ratios, reducing sample matrix effects, bringing target analytes within the linear assay detection range, among many others. Traditionally, sample processing is performed in laboratory settings through manual or automated pipetting.

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Chest computed tomography (CT) scans are essential to diagnose and monitor bronchiectasis (BE). To date, few quantitative data are available about the nature and extent of structural lung abnormalities (SLAs) on CT scans of patients with BE. To investigate SLAs on CT scans of patients with BE and the relationship of SLAs to clinical features using the EMBARC (European Multicenter Bronchiectasis Audit and Research Collaboration) registry.

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  • The study focuses on comparing the long-term quality of life (QoL) outcomes between two surgical methods for esophageal cancer: open Ivor Lewis esophagectomy (Open-E) and a hybrid approach (hRob-E) that combines laparotomy and robot-assisted surgery.
  • Patients were evaluated 36 to 40 months post-surgery using specific QoL questionnaires, revealing that both groups had similar emotional and cognitive functioning, but noticeable differences in physical functioning and pain.
  • Results suggest that while global health status remains stable post-surgery, hRob-E patients may experience better physical functioning and less pain compared to those who underwent Open-E, indicating potential advantages of the hybrid approach.
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